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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1974-9-19
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pubmed:abstractText |
Beta-glucuronidase activity was investigated during a 48-h period in which virus replication and changes in cell morphology occurred. Infection of an established line of chimpanzee liver cells with either nononcogenic adenovirus 5 or highly oncogenic adenovirus 12 under one-step growth conditions produced differing patterns of enzyme activity. There was an increase in total activity and also enhanced leakage of beta-glucuronidase from cells infected with adenovirus 12. In contrast, the enzymatic pattern of cells infected with adenovirus 5 was similar to that of uninfected cells. Hydrocortisone prevented the abnormal release of beta-glucuronidase from adenovirus 12-infected cells. The compound had no effect on total enzyme activity or on virus replication and the development of cytopathology.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-13481261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-13705510,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-13721911,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-13878255,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-14209795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-14270244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-16789093,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4194168,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4246353,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4286950,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4287123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4312695,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4350219,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-4361935,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-5000115,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-5062343,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-5437782,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4842701-5808220
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
83-7
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pubmed:dateRevised |
2010-9-10
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pubmed:meshHeading |
pubmed-meshheading:4842701-Adenoviridae,
pubmed-meshheading:4842701-Animals,
pubmed-meshheading:4842701-Cell Line,
pubmed-meshheading:4842701-Cytopathogenic Effect, Viral,
pubmed-meshheading:4842701-Glucuronidase,
pubmed-meshheading:4842701-Hydrocortisone,
pubmed-meshheading:4842701-Liver,
pubmed-meshheading:4842701-Pan troglodytes,
pubmed-meshheading:4842701-Ultrasonics,
pubmed-meshheading:4842701-Virus Replication
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pubmed:year |
1974
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pubmed:articleTitle |
Beta-glucuronidase response of cells infected with Adenovirus types 5 and 12.
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pubmed:publicationType |
Journal Article
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