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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
1
|
| pubmed:dateCreated |
1979-11-29
|
| pubmed:abstractText |
A method is described for the large-scale isolation of highly purified human growth hormone for therapeutic use. The hormone was extracted from frozen pituitary glands under mildly alkaline conditions. Purification was effected by gel filtration and ion-exchange chromatography. The final product was pyrogen-free and had a potency of 2.5 i.u./mg measured by bioassay against the current international standard. The yield of growth hormone/gland was approximately 5 mg.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0022-0795
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
82
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
77-86
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:479737-Chromatography, Gel,
pubmed-meshheading:479737-Chromatography, Ion Exchange,
pubmed-meshheading:479737-Growth Hormone,
pubmed-meshheading:479737-Humans,
pubmed-meshheading:479737-Methods,
pubmed-meshheading:479737-Pituitary Gland,
pubmed-meshheading:479737-Pyrogens,
pubmed-meshheading:479737-Technology, Pharmaceutical
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Large-scale preparation of highly purified pyrogen-free human growth hormone for clinical use.
|
| pubmed:publicationType |
Journal Article
|