rdf:type |
|
lifeskim:mentions |
umls-concept:C0003313,
umls-concept:C0003320,
umls-concept:C0024262,
umls-concept:C0033684,
umls-concept:C0205148,
umls-concept:C0205396,
umls-concept:C0332206,
umls-concept:C0871261,
umls-concept:C1533691,
umls-concept:C1704632,
umls-concept:C1704788,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
3
|
pubmed:dateCreated |
1975-8-7
|
pubmed:abstractText |
Antibody-forming cells against DNP (DNP-AFC) appear in nonantigen-stimulated cultures of spleen cells from mice which were boosted with antigen DNP-CGG or TNP-KLH in saline several weeks before the vitro cultures were started. The similar kinetics of the appearance of DNP-AFC in antigen-stimulated and non-antigen-stimulated cultures suggests that new B cells were triggered during the in vitro culture. The data supporting the concept of antigen being retained in the body for long periods of time in the form of antigen-antibody complexes on the T-cell surface is discussed.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0019-2805
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
28
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
535-42
|
pubmed:dateRevised |
2009-11-18
|
pubmed:meshHeading |
pubmed-meshheading:47837-Animals,
pubmed-meshheading:47837-Antibody Formation,
pubmed-meshheading:47837-Antibody-Producing Cells,
pubmed-meshheading:47837-Antigen-Antibody Complex,
pubmed-meshheading:47837-Antigens,
pubmed-meshheading:47837-B-Lymphocytes,
pubmed-meshheading:47837-Cell Wall,
pubmed-meshheading:47837-Cells, Cultured,
pubmed-meshheading:47837-Dinitrophenols,
pubmed-meshheading:47837-Immune Sera,
pubmed-meshheading:47837-Mice,
pubmed-meshheading:47837-Spleen,
pubmed-meshheading:47837-T-Lymphocytes,
pubmed-meshheading:47837-Trypsin,
pubmed-meshheading:47837-gamma-Globulins
|
pubmed:year |
1975
|
pubmed:articleTitle |
Blocking antigen-antibody complexes on the T-lymphocye surface identified with defined protein antigens. II. Lymphocyte activation during the in vitro response.
|
pubmed:publicationType |
Journal Article
|