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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1979-11-21
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pubmed:abstractText |
Cefazolin sodium was used to treat 20 serious bacterial infections in 19 patients, 11 of whom were infected by coagulase-positive Staphylococci. Clinical and bacteriologic success were initially obtained in 15 patients with 16 infections. 2 additional patients were cured after surgery for removal of foreign bodies and a second course of the antibiotic. 1 asplenic patient had bacteremia and died 5 days after initiating therapy with negative blood cultures and multiple abscesses. 1 patient with endocarditis relapsed 19 months after treatment with 6 weeks of cefazolin and prolonged oral antibiotics. Calculated median, trough, free drug levels were 1.5--15.3 times the minimum inhibitory concentration for 27 of 29 pathogens.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0009-3157
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
316-25
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:477454-Adult,
pubmed-meshheading:477454-Aged,
pubmed-meshheading:477454-Cefazolin,
pubmed-meshheading:477454-Drug Evaluation,
pubmed-meshheading:477454-Drug Evaluation, Preclinical,
pubmed-meshheading:477454-Female,
pubmed-meshheading:477454-Humans,
pubmed-meshheading:477454-Male,
pubmed-meshheading:477454-Microbial Sensitivity Tests,
pubmed-meshheading:477454-Middle Aged,
pubmed-meshheading:477454-Staphylococcal Infections
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pubmed:year |
1979
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pubmed:articleTitle |
Cefazolin treatment of bacterial infections. In vitro and in vivo evaluation.
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pubmed:publicationType |
Journal Article
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