Linked Life Data

47678

Source:http://linkedlifedata.com/resource/pubmed/id/47678

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1975-6-25
pubmed:abstractText
Nuclear chromatin properties in control, SV40-infected and polyoma-infected cultures of mouse embryo fibroblasts were studied using quantitative image analysis. Distribution of Feulgen-DNA-content per nucleus was found to be similar in all three groups of cultures. No differences in nuclear area, mean optical density of chromatin and area of chromatin at different optical density thresholds were measurable between control and SV40-infected fibroblasts. Polyoma-infected fibroblasts were found to have smaller nuclei, more dense and less homogeneous chromatin than non-infected cells. The changes of chromatin in polyoma-infected cells occur in G1, middle S and G2 nuclei. The results are interpreted as an early manifestation of the cytopathic effect of polyoma virus.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5547
pubmed:author
pubmed:issnType
Print
pubmed:volume
19
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
136-41
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Changes in chromatin morphology after infection of mouse embryo fibroblasts with polyoma virus, detected by image analysis.
pubmed:publicationType
Journal Article, Comparative Study, Research Support, U.S. Gov't, P.H.S.