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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1979-10-17
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pubmed:abstractText |
Mice (CD-1 strain) were placed on diets containing either municipal drinking water (Durham, North Carolina) or water that had been distilled and passed through cartridges to reduce organics and remove inorganics. After a two-week acclimation period, animals were bred and pregnancy confirmed by the presence of a sperm plug. During the 8-month course of the study, approximately 500 pregnant mice were sacrificed on day 18 of gestation and their fetuses examined for visceral and skeletal anomalies. No significant water-related effects were found on any fetal parameter studied except for a 28.1% incidence of supernumerary ribs in the tap-water group as compared to 21.1% in the purified-water group. No differences were noted in the type or occurrence of anomalies between the two groups. A month to month variation was observed in a number of parameters. The degree of variation was similar for the treatment groups, suggesting that these changes might be random fluctuations.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0040-3709
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
165-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:473070-Abnormalities, Drug-Induced,
pubmed-meshheading:473070-Animals,
pubmed-meshheading:473070-Female,
pubmed-meshheading:473070-Fetus,
pubmed-meshheading:473070-Male,
pubmed-meshheading:473070-Mice,
pubmed-meshheading:473070-Pregnancy,
pubmed-meshheading:473070-Ribs,
pubmed-meshheading:473070-Seasons,
pubmed-meshheading:473070-Water Pollutants,
pubmed-meshheading:473070-Water Pollutants, Chemical,
pubmed-meshheading:473070-Water Supply
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pubmed:year |
1979
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pubmed:articleTitle |
The fetotoxic potential of municipal drinking water in the mouse.
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pubmed:publicationType |
Journal Article,
Comparative Study
|