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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1979-10-26
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pubmed:abstractText |
The cardiac function of 21 patients with cystic fibrosis was studied using radionuclides and M-mode echocardiography. The patients (mean age 13.2 years, range 4 to 27) had a wide range of clinical and pulmonary function abnormalities (mean Shwachman-Kulczycki score 62.1). Decreased right ventricular ejection fraction was found in 13 of 18 patients (72%); an additional four patients had abnormal septal motion on ECHO. Left ventricular ejection fraction was abnormal at rest in four patients (19%); an additional four patients had borderline low LVEF. The LV pre-ejection period to ejection time ratio increased significantly (i.e., worsening LV performance) with deterioration of S-K score, chest radiograph score, and forced expiratory volume in 1 second. Three of eight patients with normal LVEF at rest had an abnormal response to supine bicycle exercise: LVEF fell in two patients and was unchanged in one. Thus evidence of LV dysfunction was observed in seven of 21 (33%) of the patients; four at rest and in three only during exercise.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-3476
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
95
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
379-84
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:469660-Adolescent,
pubmed-meshheading:469660-Adult,
pubmed-meshheading:469660-Angiography,
pubmed-meshheading:469660-Carbon Dioxide,
pubmed-meshheading:469660-Child,
pubmed-meshheading:469660-Child, Preschool,
pubmed-meshheading:469660-Cystic Fibrosis,
pubmed-meshheading:469660-Echocardiography,
pubmed-meshheading:469660-Electrocardiography,
pubmed-meshheading:469660-Female,
pubmed-meshheading:469660-Heart Ventricles,
pubmed-meshheading:469660-Humans,
pubmed-meshheading:469660-Male,
pubmed-meshheading:469660-Oxygen,
pubmed-meshheading:469660-Respiratory Function Tests
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pubmed:year |
1979
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pubmed:articleTitle |
Noninvasive evaluation of ventricular function in cystic fibrosis.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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