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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1979-10-26
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pubmed:abstractText |
The effect of 3 wk heat exposure (Ta 34 degrees C) on intestinal weight and intestinal absorption of D-glucose and D-galactose in vitro was examined in the rat. Intestinal dry weight was reduced with heat exposure compared to both ad libitum and pair-fed animals at Ta 22 degrees C. Intestinal tissue water was elevated after pair feeding but not heat exposure; extracellular (inulin) space was similar in the three groups. Mucosal uptake of glucose per gram wet weight in an everted sac preparation was unchanged compared to pair-fed animals, but serosal transfer was increased. Intestinal metabolism of glucose was decreased with heat exposure. Galactose accumulation with 30 min incubation was increased in intestinal rings from both heat-exposed and pair-fed animals. This increase is likely to be related to the reduction in ring size present in the groups with reduced food intake. Vmax and apparent Km for galactose transport were unchanged. Our results indicate that despite a reduction in intestinal weight following heat exposure, the ability of the intestine to transport hexoses per gram remains relatively stable. Alterations of hexose transport appear to be related to altered glucose metabolism and not altered transport capacity. Differences in intestinal weight and glucose utilization between pair-fed and heat-exposed animals suggest that the intestinal response to chronic heat exposure is not solely a function at the amount of food consumed. However, the alteration of more than one variable in pair feeding makes interpretation complex.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0161-7567
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
87-90
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:468678-Adaptation, Physiological,
pubmed-meshheading:468678-Animals,
pubmed-meshheading:468678-Body Weight,
pubmed-meshheading:468678-Galactose,
pubmed-meshheading:468678-Glucose,
pubmed-meshheading:468678-Growth,
pubmed-meshheading:468678-Hot Temperature,
pubmed-meshheading:468678-Intestinal Absorption,
pubmed-meshheading:468678-Intestines,
pubmed-meshheading:468678-Kinetics,
pubmed-meshheading:468678-Male,
pubmed-meshheading:468678-Rats
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pubmed:year |
1979
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pubmed:articleTitle |
Intestinal transport of hexoses in the rat following chronic heat exposure.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.
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