Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1979-10-26
|
pubmed:abstractText |
Polypyrimidine . polypurine segments are regions of duplex DNA which contain a highly asymmetric distribution of pyrimidine and purine nucleotides. A polypyrimidine in single-stranded DNA can be detected by its ability to form a complex and poly(A, G) which will bind to hydroxyapatite. We tested DNA from a variety of organisms and found that most contained polypyrimidines. From the shape of the curve relating DNA size to percentage bound to hydroxyapatite, we conclude that polypyrimidine . polypurine segments occur widely in DNA from higher organisms, at intervals of 6000--8000 base pairs throughout the majority of the genome. Lower levels occur in DNA from yeast and Drosophila.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jul
|
pubmed:issn |
0014-2956
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
98
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
301-7
|
pubmed:dateRevised |
2007-7-23
|
pubmed:meshHeading |
pubmed-meshheading:467445-Animals,
pubmed-meshheading:467445-Base Sequence,
pubmed-meshheading:467445-DNA,
pubmed-meshheading:467445-Female,
pubmed-meshheading:467445-Humans,
pubmed-meshheading:467445-Male,
pubmed-meshheading:467445-Molecular Weight,
pubmed-meshheading:467445-Nucleic Acid Hybridization,
pubmed-meshheading:467445-Polyribonucleotides,
pubmed-meshheading:467445-Purines,
pubmed-meshheading:467445-Pyrimidines,
pubmed-meshheading:467445-Species Specificity
|
pubmed:year |
1979
|
pubmed:articleTitle |
Distribution of polypyrimidine . polypurine segments in DNA from diverse organisms.
|
pubmed:publicationType |
Journal Article,
Comparative Study
|