Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1972-6-19
pubmed:abstractText
After kaolin treatment of fetal rabbit serum, 7S antibody titers were reduced more than 19S titers. This reduction was less when the kaolin treatment was performed at pH 9.0 than when it was performed at pH 7.3. A modification of the kaolin treatment of sera for use in the hemagglutination-inhibiting antibody titration, in which the hemagglutination reaction is performed at a neutral pH, is recommended. The advantage of the modified method is that adsorption of immunoglobulins to kaolin is minimized when serum is treated at a lower dilution with pH 9.0 kaolin, followed by reduction of the pH of the supernatant fluid to neutrality with a "serum adjusting diluent." When the serum was diluted with physiological saline before kaolin treatment, a great decrease in serum immunoglobulin concentrations occurred. This decrease was found to be less in the modified kaolin treatment than in the conventional pH 7.3 kaolin treatment.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0003-6919
pubmed:author
pubmed:issnType
Print
pubmed:volume
23
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
203-6
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed-meshheading:4622816-Adsorption, pubmed-meshheading:4622816-Adult, pubmed-meshheading:4622816-Animals, pubmed-meshheading:4622816-Centrifugation, Density Gradient, pubmed-meshheading:4622816-Erythrocytes, pubmed-meshheading:4622816-Female, pubmed-meshheading:4622816-Fetal Proteins, pubmed-meshheading:4622816-Hemagglutination Inhibition Tests, pubmed-meshheading:4622816-Hemolysin Proteins, pubmed-meshheading:4622816-Humans, pubmed-meshheading:4622816-Hydrogen-Ion Concentration, pubmed-meshheading:4622816-Immune Sera, pubmed-meshheading:4622816-Immunodiffusion, pubmed-meshheading:4622816-Immunoglobulin G, pubmed-meshheading:4622816-Immunoglobulin M, pubmed-meshheading:4622816-Immunoglobulins, pubmed-meshheading:4622816-Kaolin, pubmed-meshheading:4622816-Methods, pubmed-meshheading:4622816-Pregnancy, pubmed-meshheading:4622816-Rabbits, pubmed-meshheading:4622816-Rubella, pubmed-meshheading:4622816-Rubella virus, pubmed-meshheading:4622816-Sheep, pubmed-meshheading:4622816-Sucrose
pubmed:year
1972
pubmed:articleTitle
Effect of a modified kaolin treatment on serum immunoglobulins.
pubmed:publicationType
Journal Article