Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1976-6-2
pubmed:abstractText
The diffusion and uptake of two benzacridines with very similar chemical structures, but with different carcinogenic powers were investigated at the level of various organs and at the cellular level in the female rat. The chronology of the processes and lesions observed was different according to the respective carcinogenic power of the two benzacridines. On account of the small doses used, only necrotic lesions were observed, mainly in the liver and adrenal glands, but no tumorous lesions were observed. Uptake of fluorescent substance at the level of the nuclei of certain cells (submaxillaris, liver, pancreas, adrenal glands) was noticed as in previous experiments; this transient process appeared about the 100th day and lasted fairly long according to the form of benzacridine and the organ.
pubmed:language
fre
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0249-5554
pubmed:author
pubmed:issnType
Print
pubmed:volume
57
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
247-58
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1974
pubmed:articleTitle
[Uptake of methyl-12-benzo (a) and methyl-7-benzo (c) acridines by target organs of the female rat studied by fluorescence microscopy (author's transl)].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract