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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1974-4-4
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pubmed:abstractText |
Concentrated medium obtained from cultures of a continuous thymus-derived mouse lymphoma cell line (WEHI-22.1) was found to inhibit a T-cell-dependent (antidonkey red blood cell), but not a T-cell-independent (anti-DNP) immune response in vitro. Passage of such a concentrate through an anti-mouse Ig immunoadsorbent column removed its inhibitory activity. It is suggested that the tumor cell Ig can compete with specific normal T-cell Ig in its collaborative function in immune responses. A similar mechanism may account for anergy associated with some human lymphoid neoplasms.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-13193528,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4103728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4103761,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4111775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4115708,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4125686,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4126264,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4126420,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4142145,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4541405,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4546381,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4566300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-4630643,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-5439579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-5653817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-5686155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4591179-5766943
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-1007
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
139
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
785-90
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:4591179-Animals,
pubmed-meshheading:4591179-Antibody Formation,
pubmed-meshheading:4591179-Antigen-Antibody Complex,
pubmed-meshheading:4591179-B-Lymphocytes,
pubmed-meshheading:4591179-Binding Sites, Antibody,
pubmed-meshheading:4591179-Cell Line,
pubmed-meshheading:4591179-Cytotoxicity Tests, Immunologic,
pubmed-meshheading:4591179-Hemolytic Plaque Technique,
pubmed-meshheading:4591179-Immune Tolerance,
pubmed-meshheading:4591179-Mice,
pubmed-meshheading:4591179-Mice, Inbred BALB C,
pubmed-meshheading:4591179-Mice, Inbred C57BL,
pubmed-meshheading:4591179-Mice, Inbred CBA,
pubmed-meshheading:4591179-Mice, Inbred Strains,
pubmed-meshheading:4591179-Neoplasms, Experimental,
pubmed-meshheading:4591179-Perissodactyla,
pubmed-meshheading:4591179-Rabbits,
pubmed-meshheading:4591179-Spleen,
pubmed-meshheading:4591179-T-Lymphocytes,
pubmed-meshheading:4591179-Thymoma,
pubmed-meshheading:4591179-Thymus Neoplasms
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pubmed:year |
1974
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pubmed:articleTitle |
Inhibition of a T-cell-dependent immune response in vitro by thymoma cell immunoglobulin.
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pubmed:publicationType |
Journal Article
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