Linked Life Data

458788

Source:http://linkedlifedata.com/resource/pubmed/id/458788

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1979-9-17
pubmed:abstractText
The active agent in crude or extracted materials from patients with acute rheumatoid arthritis (RA), when injected into embryonated eggs, produced an increased percentage of characteristic "crooked toe" defects in the bioassay. Experimental RA chick materials also produced these defects. A protein-free ribonucleic acid extract from RA synovia and joint fluids of patients with acute or subacute classical RA produced the same experimental RA lesions as did the crude materials, but non-RA materials and controls did not. The injected RA material produced the "crooked toe" disease in chicks in direct proportion to the clinically diagnosed severity of the RA in the patient, and inversely with dilution.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
6
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
135-46
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Further studies on the specific infectious agent isolated in rheumatoid arthritis.
pubmed:publicationType
Journal Article