| pubmed-article:4579014 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C0521009 | lld:lifeskim |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C0439849 | lld:lifeskim |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C0023810 | lld:lifeskim |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C1156237 | lld:lifeskim |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C1510811 | lld:lifeskim |
| pubmed-article:4579014 | lifeskim:mentions | umls-concept:C0678594 | lld:lifeskim |
| pubmed-article:4579014 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:4579014 | pubmed:dateCreated | 1973-10-9 | lld:pubmed |
| pubmed-article:4579014 | pubmed:abstractText | The ability of bacterial lipopolysaccharides to induce lymphocyte mitogenesis and to act as an adjuvant of antibody formation was attributable to the lipid-A region of the molecule. Measured by induction of DNA synthesis, lipid A was mitogenic for bone marrow-derived lymphocytes obtained from spleens of congenitally athymic mice but not for thymocytes obtained from thymuses of normal mice. Adjuvanticity was demonstrated by the ability of lipid A to convert a tolerogenic regimen of antigen into one eliciting an immune response and by its ability to markedly enhance the antibody response to a weak antigen. | lld:pubmed |
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| pubmed-article:4579014 | pubmed:language | eng | lld:pubmed |
| pubmed-article:4579014 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:4579014 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4579014 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4579014 | pubmed:month | Jul | lld:pubmed |
| pubmed-article:4579014 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:4579014 | pubmed:author | pubmed-author:MorrisonD CDC | lld:pubmed |
| pubmed-article:4579014 | pubmed:author | pubmed-author:WeigleW OWO | lld:pubmed |
| pubmed-article:4579014 | pubmed:author | pubmed-author:ChillerJ MJM | lld:pubmed |
| pubmed-article:4579014 | pubmed:author | pubmed-author:SkidmoreB JBJ | lld:pubmed |
| pubmed-article:4579014 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4579014 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:4579014 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4579014 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4579014 | pubmed:pagination | 2129-33 | lld:pubmed |
| pubmed-article:4579014 | pubmed:dateRevised | 2010-9-10 | lld:pubmed |
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| pubmed-article:4579014 | pubmed:year | 1973 | lld:pubmed |
| pubmed-article:4579014 | pubmed:articleTitle | Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. | lld:pubmed |
| pubmed-article:4579014 | pubmed:publicationType | Journal Article | lld:pubmed |
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