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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1973-9-21
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pubmed:abstractText |
Analysis of the partition in a two-polymer phase system of Salmonella typhimurium R mutants with different susceptibility to phagocytosis distinguished between the mutants. Close to 80% of the R mutants least resistant to phagocytosis accumulated in the dextran-rich phase, whereas more phagocytosis-resistant mutants showed higher affinity for the interface and the polyethylene glycol-rich top phase. By growing the uridine diphosphate (pyro)-gal-4-epimeraseless mutant LT2-M1 in the presence of d-galactose for different periods of time, two well-defined peaks were obtained in counter-current distribution analysis with an aqueous two-polymer phase system revealing a heterogeneous population in the culture. One peak was located at a site characteristic of R bacteria, the other at the site of S bacteria. As growth proceeded, more bacteria transferred from the R-type to the S-type peak. Within each peak, a gradual increase in resistance to phagocytosis by rabbit polymorphonuclear cells occurred with increasing length of growth in d-galactose.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-16557701,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4403781,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4566178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4586859,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4866005,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4896244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4911545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4915250,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4922339,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4578150-4985271
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0019-9567
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-41
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading | |
pubmed:year |
1973
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pubmed:articleTitle |
Partition of Salmonella typhimurium in a two-polymer acqueous phase system in relation to liability to phagocytosis.
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pubmed:publicationType |
Journal Article
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