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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1972-10-25
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pubmed:abstractText |
The effect of preincubation with anti-theta or anti-mouse immunoglobulin (Ig) and complement (C') on immune responsiveness of spleen cells from BALB/c mice immunized with sheep erythrocytes (SE) was investigated. Both treatments greatly depressed the remaining ability to produce a secondary response to SE in vitro. Normal BALB/c spleen cells were far less effective in reconstituting the responses of such depleted cell populations than were much smaller numbers of untreated immune spleen cells. Thymus-derived cell (T cell) memory appeared early after immunization and showed specificity for the immunizing antigens. Recombination of anti-Ig-treated with anti-theta-treated immune spleen cells resulted in virtually complete reconstitution of responsiveness. The presence of immunological memory in T cells and the nature of their surface receptors are discussed.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-15776565,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4097588,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4101345,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4102685,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4103326,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4106485,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4108426,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4109111,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4109807,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4110524,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4110525,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4190860,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4190976,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4192568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4193208,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4385242,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4396811,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4399419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4551279,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4551579,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4551582,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4626849,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4919141,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4920655,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4923852,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4938447,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4940620,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4943358,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4944187,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-4990555,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5000986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5060295,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5065602,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5065603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5089508,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5103556,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5112202,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5282893,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5305572,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5313314,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5315413,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5534449,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-5534450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4560343-6034749
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0022-1007
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
136
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
663-75
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pubmed:dateRevised |
2010-6-22
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pubmed:meshHeading |
pubmed-meshheading:4560343-Animals,
pubmed-meshheading:4560343-Antibody Formation,
pubmed-meshheading:4560343-Antibody-Producing Cells,
pubmed-meshheading:4560343-Antigens,
pubmed-meshheading:4560343-Bone Marrow,
pubmed-meshheading:4560343-Bone Marrow Cells,
pubmed-meshheading:4560343-Cell Membrane,
pubmed-meshheading:4560343-Cells, Cultured,
pubmed-meshheading:4560343-Complement System Proteins,
pubmed-meshheading:4560343-Erythrocytes,
pubmed-meshheading:4560343-Hemolytic Plaque Technique,
pubmed-meshheading:4560343-Immune Sera,
pubmed-meshheading:4560343-Immunity, Maternally-Acquired,
pubmed-meshheading:4560343-Immunoglobulin G,
pubmed-meshheading:4560343-Immunologic Memory,
pubmed-meshheading:4560343-Immunosuppression,
pubmed-meshheading:4560343-Leukemia, Experimental,
pubmed-meshheading:4560343-Lymphocytes,
pubmed-meshheading:4560343-Male,
pubmed-meshheading:4560343-Mice,
pubmed-meshheading:4560343-Sheep,
pubmed-meshheading:4560343-Spleen,
pubmed-meshheading:4560343-Thymus Gland
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pubmed:year |
1972
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pubmed:articleTitle |
Surface antigens of immunocompetent cells. 3. In vitro studies of the role of B and T cells in immunological memory.
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