Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1979-9-25
pubmed:abstractText
Experiments were carried out on the papillary muscles prepared from the rabbit heart 10, 60 or 180 minutes after exposure of the animals to thermal burn. Isometric tension in the changing stimulation frequency of the preparation (the range being 0.1-2.0 Hz) and in post-stimulating potentiation was recorded. It was shown that the disturbance degree of the myocardial contractile activity caused by the burn rose depending on increased shock duration. It was evidenced by the following findings: in all the papillary muscles prepared 3 hours after burn and in 50% of the preparations taken one hour after the injury the "biphasic" dependence frequency power (F-P) peculiar to healthy myocardium changed to "monophasic" one (contraction amplitude progressively decreased on the frequency growing), and poststimulating potentiation, absent in the normal myocardium state, appeared. Within 10-minute shock duration only several preparations revealed poststimulating potentiation, F-P changes being absent. Normal rhythmoinotropic relationships in the myocardium restored under the influence of two-fol increase of (Ca2+)o or under prolonged (3-4 hours) perfusion of the preparation with normal Tyrode's solution. The changes observed in the myocardium rhythmoinotropic relationships produced by the burn shock were similar to those occurred as a result of the calcium canals block by the compound D-600.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0365-9615
pubmed:author
pubmed:issnType
Print
pubmed:volume
87
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
402-5
pubmed:dateRevised
2008-10-8
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
[Change in the contractile activity of the rabbit myocardium as a result of burn shock of different duration].
pubmed:publicationType
Journal Article, English Abstract