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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1979-9-1
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pubmed:abstractText |
The 1,659 non-leprous people in a Micronesian population experiencing an annual leprosy incidence rate of about 7/1,000 were offered 15 acedapsone (DADDS) injections during 1967--1970 for leprosy prevention purposes. Subsequent annual surveillance showed an initial cessation of new cases during the 3-year DADDS campaign, followed by a resumption of cases thereafter at a yearly level of about 2/1,000 with a longer pause and slower rise among those who received the full regimen. A secondary wave of cases that has occurred since 1973 among children born after 1968 shows that post-campaign transmission occurred, probably principally from relapsing multibacillary cases with onset before the campaign. Recommendations are made for a balanced, long-term control program with DADDS preventive treatment limited to contacts of multibacillary cases.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0002-9637
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
559-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:453449-Acedapsone,
pubmed-meshheading:453449-Adult,
pubmed-meshheading:453449-Child,
pubmed-meshheading:453449-Dapsone,
pubmed-meshheading:453449-Drug Resistance, Microbial,
pubmed-meshheading:453449-Humans,
pubmed-meshheading:453449-Leprosy,
pubmed-meshheading:453449-Micronesia,
pubmed-meshheading:453449-Patient Compliance,
pubmed-meshheading:453449-Recurrence
|
pubmed:year |
1979
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pubmed:articleTitle |
Acedapsone in the prevention of leprosy: field trial in three high prevalence villages in Micronesia.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|