Linked Life Data

45299

Source:http://linkedlifedata.com/resource/pubmed/id/45299

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1981-3-24
pubmed:abstractText
Six putative neurotransmitters and the beta-receptor excitant isoproterenol were applied to bulbar respiratory neurons classified according to their burst discharge in the respiratory cycle and, for comparison, also to "unspecific" cells. With glycine inhibition occurred in I and prevailed in unspecific neurons. With GABA inhibition preponderated in I and E neurons. Glutamate excited E neurons. With dopamine inhibition prevailed in I and unspecific neurons. The majority of E neurons remained unaffected. With NE excitation occurred in EI and preponderated in I, IE, E and unspecific neurons, while some IE and E neurons were inhibited. The effects of isoproterenol did not allow any clear statement about receptor properties. In I units, however, activation was more frequent than inhibition. With 5-HT excitation prevailed in IE neurons. About half of the I cells remained unaffected and in the remainder inhibition preponderated over activation. This suggests the existence of two 5-HT-specific receptors in I and IE neurons. Comparison of the single effects revealed differences in the receptor properties of the various cell types. Results suggest that some cell types possess dopaminergic receptors and that these differ from NE-receptors, which have been found in all cell types. NE-receptor stimulation apparently can result in neuronal activation or inhibition.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0003-9829
pubmed:author
pubmed:issnType
Print
pubmed:volume
117
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-12
pubmed:dateRevised
2009-10-5
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Microelectrophoretic application of putative neurotransmitters onto various types of bulbar respiratory neurons.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't