4525300

Source:http://linkedlifedata.com/resource/pubmed/id/4525300

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0013227, umls-concept:C0019935, umls-concept:C0030956, umls-concept:C0032017, umls-concept:C0441655, umls-concept:C0449445, umls-concept:C0683598, umls-concept:C1707689
pubmed:issue	5
pubmed:dateCreated	1974-8-23
pubmed:abstractText	Stepwise, synthetic alteration of oxytocin, guided by conformational and enzymological considerations, has led to analogs with specifically modified activity profiles and resistance to enzymatic inactivation. General requirements for the design of peptides with therapeutic value are discussed.
pubmed:commentsCorrections	http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-13586222, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-13856186, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-13996119, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-14019993, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-14255161, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-14448781, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-4356942, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-4505670, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-4622083, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5028155, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5032960, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5280529, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5283296, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5288386, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5337372, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5453287, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-5685578, http://linkedlifedata.com/resource/pubmed/commentcorrection/4525300-6023591
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7505876
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Oxytocics, http://linkedlifedata.com/resource/pubmed/chemical/Peptides, http://linkedlifedata.com/resource/pubmed/chemical/Vasoconstrictor Agents
pubmed:status	MEDLINE
pubmed:month	May
pubmed:issn	0027-8424
pubmed:author	pubmed-author:SakakibaraSS, pubmed-author:WalterRR, pubmed-author:YamanakaTT
pubmed:issnType	Print
pubmed:volume	71
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1901-5
pubmed:dateRevised	2009-11-18
pubmed:meshHeading	pubmed-meshheading:4525300-Animals, pubmed-meshheading:4525300-Catalysis, pubmed-meshheading:4525300-Chemical Phenomena, pubmed-meshheading:4525300-Chemistry, pubmed-meshheading:4525300-Depression, Chemical, pubmed-meshheading:4525300-Diuresis, pubmed-meshheading:4525300-Female, pubmed-meshheading:4525300-Lactation, pubmed-meshheading:4525300-Male, pubmed-meshheading:4525300-Molecular Conformation, pubmed-meshheading:4525300-Oxytocics, pubmed-meshheading:4525300-Peptides, pubmed-meshheading:4525300-Pregnancy, pubmed-meshheading:4525300-Rabbits, pubmed-meshheading:4525300-Rats, pubmed-meshheading:4525300-Stimulation, Chemical, pubmed-meshheading:4525300-Vasoconstrictor Agents
pubmed:year	1974
pubmed:articleTitle	A neurohypophyseal hormone analog with selective oxytocin-like activities and resistance to enzymatic inactivation: an approach to the design of peptide drugs.
pubmed:publicationType	Journal Article