|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
5
|
|
pubmed:dateCreated |
1979-9-1
|
|
pubmed:abstractText |
We investigated the relationship between prolactin content and DNA replication in the anterior pituitary gland. Thymidine incorporation in pregnant rats is significantly lower than in virgin controls. This is accompanied by a decreased activity of DNA polymerase. Sulpiride administration to pregnant rats enhances thymidine incorporation to levels similar to virgin controls. The results indicate a negative feedback between prolactin content and DNA synthesis in the rat anterior pituitary gland.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0014-4754
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
35
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
689-90
|
|
pubmed:dateRevised |
2003-11-14
|
|
pubmed:meshHeading |
pubmed-meshheading:446682-Animals,
pubmed-meshheading:446682-Cell Division,
pubmed-meshheading:446682-DNA,
pubmed-meshheading:446682-DNA Replication,
pubmed-meshheading:446682-DNA-Directed DNA Polymerase,
pubmed-meshheading:446682-Endonucleases,
pubmed-meshheading:446682-Female,
pubmed-meshheading:446682-Pituitary Gland, Anterior,
pubmed-meshheading:446682-Pregnancy,
pubmed-meshheading:446682-Prolactin,
pubmed-meshheading:446682-Rats,
pubmed-meshheading:446682-Thymidine Kinase
|
|
pubmed:year |
1979
|
|
pubmed:articleTitle |
Cell proliferation in the rat pituitary gland: a mechanism of control in prolactin cells.
|
|
pubmed:publicationType |
Journal Article
|
