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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
1979-7-25
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pubmed:abstractText |
In 16 rabbits with bilateral corneal burns, indomethacin was administered topically to one eye on each day after the lesion was made to determine the effect of a prostaglandin inhibitor on the corneal neovascular response to experimental thermal burns. Comparison of the two eyes showed a reduction of both hyperemia and neovascularization in indomethacin-treated eyes during the first five days after injury. Histologic observations during this period showed a reduction in polymorphonuclear cell infiltration in the treated corneas. Inhibition of prostaglandin synthesis by indomethacin apparently led to a reduction in the inflammatory response and the subsequent corneal neovascularization.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0002-9394
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
87
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
536-40
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pubmed:dateRevised |
2003-11-14
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pubmed:meshHeading |
pubmed-meshheading:443319-Animals,
pubmed-meshheading:443319-Capillaries,
pubmed-meshheading:443319-Cornea,
pubmed-meshheading:443319-Eye Burns,
pubmed-meshheading:443319-Hyperemia,
pubmed-meshheading:443319-Indomethacin,
pubmed-meshheading:443319-Prostaglandin Antagonists,
pubmed-meshheading:443319-Rabbits,
pubmed-meshheading:443319-Wound Healing
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pubmed:year |
1979
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pubmed:articleTitle |
Suppressive effects of indomethacin on thermally induced neovascularization of rabbit corneas.
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pubmed:publicationType |
Journal Article
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