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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1979-7-28
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pubmed:abstractText |
The IgA system in a patient with SCID and ADA deficiency showed heterogeneity. Serum IgA and stool secretory IgA (SIgA) levels were normal, but with altered kappa/lambda and A1/A2 subclass ratios; IgA in saliva and urine was deficient. Amounts of secretory component were normal. Jejunal and rectal biopsies showed prominent lymphonodular hyperplasia, but no cells containing IgA. A normal serum IgA level therefore does not always predict an intact secretory IgA system.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0001-656X
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
68
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
453-8
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pubmed:dateRevised |
2009-11-11
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pubmed:meshHeading |
pubmed-meshheading:443046-Adenosine Deaminase,
pubmed-meshheading:443046-Age Factors,
pubmed-meshheading:443046-Child, Preschool,
pubmed-meshheading:443046-Feces,
pubmed-meshheading:443046-Female,
pubmed-meshheading:443046-Humans,
pubmed-meshheading:443046-Hyperplasia,
pubmed-meshheading:443046-Immunoglobulin A,
pubmed-meshheading:443046-Immunoglobulin A, Secretory,
pubmed-meshheading:443046-Immunoglobulin G,
pubmed-meshheading:443046-Immunoglobulin M,
pubmed-meshheading:443046-Immunologic Deficiency Syndromes,
pubmed-meshheading:443046-Infant,
pubmed-meshheading:443046-Lymph Nodes,
pubmed-meshheading:443046-Nucleoside Deaminases,
pubmed-meshheading:443046-Radioimmunoassay,
pubmed-meshheading:443046-Saliva
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pubmed:year |
1979
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pubmed:articleTitle |
Regional deficiency of secretory IgA in a patient with combined immunodeficiency of the ADA deficient type.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Case Reports
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