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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1979-7-16
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pubmed:abstractText |
The urine sediment of 12 geriatric patients with indwelling catheters was quantified by the glutaraldehyde-cytocentrifuge method prior to, during and after a clinical trial of methenamine hippurate (MH), 2 g x 3 daily given for 34 days as the sole therapeutic agent for the urinary tract infection. The median leukocyte concentration in the urine of these patients was 100 cells/microliter (Q1 - Q3 50-350), i.e. tenfold higher than the upper normal limits reported in healthy probands. The median bacteriuria in the control period was 12 x 10(5) bacteria/ml urine, interquartile range 10-60 x 10(5) bacteria/ml and extreme individual values 300-500 x 10(5) bacteria/ml. Hematuria, defined as greater than or equal to 24 erythrocytes/microliter urine, was not prominent and could not be correlated with MH treatment, nor with catheter changes. The reported observations suggest that short-term high-dose treatment with MH as sole therapeutic agent reduced pyruria and bacteriuria in the group of patients studied.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9734
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
84
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
75-82
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:442280-Aged,
pubmed-meshheading:442280-Bacteriuria,
pubmed-meshheading:442280-Catheters, Indwelling,
pubmed-meshheading:442280-Drug Evaluation,
pubmed-meshheading:442280-Hippurates,
pubmed-meshheading:442280-Humans,
pubmed-meshheading:442280-Leukocyte Count,
pubmed-meshheading:442280-Methenamine,
pubmed-meshheading:442280-Pyuria,
pubmed-meshheading:442280-Time Factors,
pubmed-meshheading:442280-Urinary Catheterization,
pubmed-meshheading:442280-Urinary Tract Infections
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pubmed:year |
1979
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pubmed:articleTitle |
The effect of short-term high-dose treatment with methenamine hippurate of urinary infection in geriatric patients with indwelling catheters. II. Evaluation by means of a quantified urine sediment.
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pubmed:publicationType |
Journal Article
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