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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
33
|
| pubmed:dateCreated |
1972-7-21
|
| pubmed:abstractText |
Foreskins from children who were circumcised 2 to 4 days after birth contain an enzyme system that hydroxylates the carcinogen benzo[alpha]pyrene. When foreskin was cultured for 16 hours in the presence of 10 micromolar benz[alpha]anthracene, a two- to fivefold increase in activity of benzo[alpha]pyrene hydroxylase was obtained. An evaluation of the basal activity and inducibility of carcinogen-metabolizing enzymes in human tissues may provide a means of determining the ability of different individuals to metabolize carcinogens.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Apr
|
| pubmed:issn |
0036-8075
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:day |
28
|
| pubmed:volume |
176
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
419-20
|
| pubmed:dateRevised |
2007-8-17
|
| pubmed:meshHeading |
pubmed-meshheading:4402068-Benz(a)Anthracenes,
pubmed-meshheading:4402068-Benzopyrenes,
pubmed-meshheading:4402068-Culture Techniques,
pubmed-meshheading:4402068-Enzyme Induction,
pubmed-meshheading:4402068-Humans,
pubmed-meshheading:4402068-Infant, Newborn,
pubmed-meshheading:4402068-Male,
pubmed-meshheading:4402068-Mixed Function Oxygenases,
pubmed-meshheading:4402068-NADP,
pubmed-meshheading:4402068-Penis,
pubmed-meshheading:4402068-Skin
|
| pubmed:year |
1972
|
| pubmed:articleTitle |
Induction of benzo( )pyrene hydroxylase in human skin.
|
| pubmed:publicationType |
Journal Article
|