| pubmed-article:436117 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0227525 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0014406 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0012899 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0038960 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:436117 | lifeskim:mentions | umls-concept:C0599787 | lld:lifeskim |
| pubmed-article:436117 | pubmed:issue | 4-5 | lld:pubmed |
| pubmed-article:436117 | pubmed:dateCreated | 1979-7-28 | lld:pubmed |
| pubmed-article:436117 | pubmed:abstractText | Unscheduled DNA synthesis was induced by 3,3'4,4'-tetrachloroazobenzene (TCAB)) in freshly isolated suspensions of rat hepatocytes. A dose-dependent response was demonstrated. Hepatocellular DNA was obtained after the chloroform-isoamyl alchohol-phenol extraction of the isolated nuclei. The induction of unscheduled DNA synthesis was measured by the incorporation of [3H]-thymidine in the presence of hydroxyurea as determined by the scintillation counting assay. DNA repair data obtained in this study on benzo[a]pyrene and methyl methanesulfonate are comparable to a previous report using primary cultures of hepatocytes and cesium chloride gradients. Hence, the present method offers promise as a rapid and sensitive screen for chemical carcinogens. | lld:pubmed |
| pubmed-article:436117 | pubmed:language | eng | lld:pubmed |
| pubmed-article:436117 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:436117 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:436117 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:436117 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:436117 | pubmed:issn | 0304-3835 | lld:pubmed |
| pubmed-article:436117 | pubmed:author | pubmed-author:JostDD | lld:pubmed |
| pubmed-article:436117 | pubmed:author | pubmed-author:KreamerB LBL | lld:pubmed |
| pubmed-article:436117 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:436117 | pubmed:volume | 6 | lld:pubmed |
| pubmed-article:436117 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:436117 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:436117 | pubmed:pagination | 207-12 | lld:pubmed |
| pubmed-article:436117 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-A... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-L... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-R... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-B... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-A... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-C... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-D... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-M... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-C... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-M... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-D... | lld:pubmed |
| pubmed-article:436117 | pubmed:meshHeading | pubmed-meshheading:436117-D... | lld:pubmed |
| pubmed-article:436117 | pubmed:year | 1979 | lld:pubmed |
| pubmed-article:436117 | pubmed:articleTitle | Induction of unscheduled DNA synthesis in suspensions of rat hepatocytes by an environmental toxicant, 3,3'4,4'-tetrachloroazobenzene. | lld:pubmed |
| pubmed-article:436117 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:436117 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:436117 | pubmed:publicationType | In Vitro | lld:pubmed |
| pubmed-article:436117 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
