Linked Life Data

435414

Source:http://linkedlifedata.com/resource/pubmed/id/435414

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1979-7-28
pubmed:abstractText
Plasma renin and angiotensin II levels were measured in nine patients immediately before and at half-hourly intervals in the four hours following therapeutic termination of pregnancy. There was a small fall in renin and angiotensin II levels over the first 1 to 2 hours, followed by a slight increase. The magnitude of these effects was much smaller than those previously seen following normal delivery. It is concluded that in early pregnancy maternal, rather than feto-placental, factors are controlling the renin-angiotensin system.
pubmed:keyword
http://linkedlifedata.com/resource/pubmed/keyword/ABORTION, THERAPEUTIC, http://linkedlifedata.com/resource/pubmed/keyword/Abortion, Induced, http://linkedlifedata.com/resource/pubmed/keyword/Age Factors, http://linkedlifedata.com/resource/pubmed/keyword/BLOOD PRESSURE, http://linkedlifedata.com/resource/pubmed/keyword/Biology, http://linkedlifedata.com/resource/pubmed/keyword/Clinical Research, http://linkedlifedata.com/resource/pubmed/keyword/Family Planning, http://linkedlifedata.com/resource/pubmed/keyword/Fertility Control, Postconception, http://linkedlifedata.com/resource/pubmed/keyword/HOMEOSTASIS, http://linkedlifedata.com/resource/pubmed/keyword/Parity, http://linkedlifedata.com/resource/pubmed/keyword/Physiology, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, http://linkedlifedata.com/resource/pubmed/keyword/Pregnancy, First Trimester, http://linkedlifedata.com/resource/pubmed/keyword/Renal Effects, http://linkedlifedata.com/resource/pubmed/keyword/Renin-angiotensin-aldosterone Effects, http://linkedlifedata.com/resource/pubmed/keyword/Reproduction, http://linkedlifedata.com/resource/pubmed/keyword/Research Methodology
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0306-5456
pubmed:author
pubmed:issnType
Print
pubmed:volume
86
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
285-9
pubmed:dateRevised
2004-11-17
pubmed:otherAbstract
PIP: To determine the effect of therapeutic abortion on the activity of the reninangiotensin system, 9 patients were immediately evaluated before, and during the 1st 4 hours after, pregnancy was terminated. Data on parity, patient's age, fetal gestational age, and initiatial blood pressure were obtained. The patients were given an intravenous infusion of 5% dextrose at a rate of 30 drops/minute using an indwelling teflon cannula. Abortions were induced by suction evacuation of uterine contents by a Clements pump following administration of paracervical block. Overall, a highly significant correlation was observed between plasma renin activity and concentration (r=0.7381; p .001), between plasma renin activity and angiotensin 2 (n=.3397; p .005) and between plasma renin concentration and angiotensin 2 (r=3603; p .001). Also noted was a significant inverse relationship between diastolic blood pressure and simultaneously measured angiotensin 2 levels (r=-.493; p .001), indirectly supporting the hypothesis that maternal, rather than feto-placental factors, control the renin-angiotensin system during the 1st trimester pregnancy. For a better understanding of feto-placental 'pregnancy renin', it is important to differentiate between renal and 'pregnancy renin'.
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Sequential changes in the human renin-angiotensin system following therapeutic termination of pregnancy.
pubmed:publicationType
Journal Article