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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1972-1-10
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pubmed:abstractText |
The indirect immunofluorescence technique demonstrated that human alpha fetoprotein (AFP) was present in a focal pattern in the cytoplasm of malignant liver cells of patients whose sera contained AFP. A few fibroblastlike cells in tissue culture of liver biopsies from patients with hepato-cellular carcinoma and AFP in their sera also had the protein. The intracellular localisation of human AFP was confirmed by centrifugation of washed, homogenised and ultra-sonically disrupted neonatal liver cells. Examination of livers of fetuses and neonates showed that AFP was present predominantly in the periportal parenchymal cells.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4166690,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4170567,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4174340,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4176107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4181585,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4182837,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4188217,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4316951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4970710,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-4975061,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-5365344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4329952-5717566
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0007-0920
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
343-9
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pubmed:dateRevised |
2011-7-20
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pubmed:meshHeading |
pubmed-meshheading:4329952-Adult,
pubmed-meshheading:4329952-Aged,
pubmed-meshheading:4329952-Animals,
pubmed-meshheading:4329952-Biopsy,
pubmed-meshheading:4329952-Carcinoma, Hepatocellular,
pubmed-meshheading:4329952-Cells, Cultured,
pubmed-meshheading:4329952-Centrifugation,
pubmed-meshheading:4329952-Child,
pubmed-meshheading:4329952-Culture Techniques,
pubmed-meshheading:4329952-Cytoplasm,
pubmed-meshheading:4329952-Female,
pubmed-meshheading:4329952-Fetal Proteins,
pubmed-meshheading:4329952-Fetus,
pubmed-meshheading:4329952-Fibroblasts,
pubmed-meshheading:4329952-Fluorescent Antibody Technique,
pubmed-meshheading:4329952-Humans,
pubmed-meshheading:4329952-Infant,
pubmed-meshheading:4329952-Infant, Newborn,
pubmed-meshheading:4329952-Liver,
pubmed-meshheading:4329952-Liver Neoplasms,
pubmed-meshheading:4329952-Male,
pubmed-meshheading:4329952-Middle Aged,
pubmed-meshheading:4329952-Rabbits,
pubmed-meshheading:4329952-Ultrasonics
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pubmed:year |
1971
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pubmed:articleTitle |
Immunofluorescent localisation of human alpha feto-protein in fetal and neonatal livers and cultured cells from hepatocellular carcinoma.
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pubmed:publicationType |
Journal Article
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