Linked Life Data

4321391

Source:http://linkedlifedata.com/resource/pubmed/id/4321391

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
968
pubmed:dateCreated
1971-2-10
pubmed:abstractText
Herpesviruses specify new glycoproteins that bind to cell membranes and also appear in the envelope of the virion. Incubation of purified smooth membranes from infected cells with antiviral antibody results in an increase in the density of the membranes as determined by flotation in sucrose density gradients. The magnitude of this increase depends on the amount of antibody used; densities as high as 1.16 grams per cubic centimeter have been obtained (the density of the untreated membranes is 1.08 grams per cubic centimeter). Antiviral antibody does not increase the density of uninfected cell membranes nor do saline or normal rabbit serum change the densities of infected or uninfected cell mnembranes. Viral antigens-presumably the glycoproteins specified by the virus-are probably on the surface of the infected cell membranes and bind to them strongly enough to withstand the hydrodynamic forces applied to them in the sucrose gradient.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0036-8075
pubmed:author
pubmed:issnType
Print
pubmed:day
22
pubmed:volume
171
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
298-300
pubmed:dateRevised
2007-8-17
pubmed:meshHeading
pubmed:year
1971
pubmed:articleTitle
Herpesvirus antigens on cell membranes detected by centrifugation of membrane-antibody complexes.
pubmed:publicationType
Journal Article