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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
966
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pubmed:dateCreated |
1971-2-9
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pubmed:abstractText |
A major polar metabolite of cholecalciferol (vitamin D(3)) obtained from chick intestines is over four times as effective as cholecalciferol and over two times as effective as 25-hydroxycholecalciferol in stimulating intestinal calcium transport 24 hours after administration. Following a considerable lag, cholecalciferol and its 25-hydroxy derivative produce a maximum stimulation of the transport response at 24 to 48 hours. The polar intestinal metabolite greatly shortens this lag, stimulating maximum calcium transport by 9 hours. At 9 hours this metabolite is at least 13 times as active as the parent cholecalciferol and as such is a likely candidate for the biologically active form of cholecalciferol in the intestine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0036-8075
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
8
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pubmed:volume |
171
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
79-82
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pubmed:dateRevised |
2007-8-17
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pubmed:meshHeading | |
pubmed:year |
1971
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pubmed:articleTitle |
Vitamin D: A cholecalciferol metabolite highly active in promoting intestinal calcium transport.
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pubmed:publicationType |
Journal Article
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