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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1970-1-24
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pubmed:abstractText |
1. The relative efficiencies of nicotinate, quinolinate and nicotinamide as precursors of NAD(+) were measured in the first leaf of barley seedlings. 2. In small amounts, both [(14)C]nicotinate and [(14)C]quinolinate were quickly and efficiently incorporated into NAD(+) and some evidence is presented suggesting that NAD(+) is formed from each via nicotinic acid mononucleotide and deamido-NAD. 3. [(14)C]Nicotinamide served equally well as a precursor of NAD(+) and although significant amounts of [(14)C]NMN were detected, most of the [(14)C]NAD(+) was derived from nicotinate intermediates formed by deamination of [(14)C]nicotinamide. 4. Radioactive NMN was also a product of the metabolism of [(14)C]nicotinate and [(14)C]quinolinate but most probably it arose from the breakdown of [(14)C]NAD(+). 5. In barley leaves where the concentration of NAD(+) is markedly increased by infection with Erysiphe graminis, the pathways of NAD(+) biosynthesis did not appear to be altered after infection. A comparison of the rates of [(14)C]NAD(+) formation in infected and non-infected leaves indicated that the increase in NAD(+) content was not due to an increased rate of synthesis.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-13563526,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-13563527,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-13790768,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-13901009,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-14085389,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-14275155,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-14284754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-14347932,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-16656827,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4288130,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4288134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4288535,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4289925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4291905,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4294854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4296054,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4296374,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4298234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4300552,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-4306794,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4311439-5856607
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0264-6021
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
115
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
679-85
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pubmed:dateRevised |
2010-9-10
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pubmed:meshHeading |
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pubmed:year |
1969
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pubmed:articleTitle |
Nicotinate, quinolinate and nicotinamide as precursors in the biosynthesis of nicotinamide-adenine dinucleotide in barley.
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pubmed:publicationType |
Journal Article
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