| pubmed-article:4309595 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4309595 | lifeskim:mentions | umls-concept:C0030738 | lld:lifeskim |
| pubmed-article:4309595 | lifeskim:mentions | umls-concept:C0026237 | lld:lifeskim |
| pubmed-article:4309595 | lifeskim:mentions | umls-concept:C0022157 | lld:lifeskim |
| pubmed-article:4309595 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:4309595 | lifeskim:mentions | umls-concept:C1280500 | lld:lifeskim |
| pubmed-article:4309595 | lifeskim:mentions | umls-concept:C0376259 | lld:lifeskim |
| pubmed-article:4309595 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:4309595 | pubmed:dateCreated | 1969-11-4 | lld:pubmed |
| pubmed-article:4309595 | pubmed:abstractText | 1. The effect of pH on the co-operative activation of the NAD-specific isocitrate dehydrogenase from pea mitochondria by isocitrate is shown. 2. The interlinked effects of pH on the affinity of the NAD-specific isocitrate dehydrogenase for isocitrate and the dependence of the pH optimum on the substrate concentration are presented. 3. A consideration of the conditions of pH and substrate concentration under which citrate activates the NAD-specific isocitrate dehydrogenase demonstrates similarities between the binding of isocitrate and citrate. 4. A comparison of the effects of citrate and pH on the gross structure of the enzyme is investigated by density-gradient centrifugation. 5. The kinetic interpretations of these results are briefly considered. 6. The metabolic significance of these studies is discussed. | lld:pubmed |
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| pubmed-article:4309595 | pubmed:language | eng | lld:pubmed |
| pubmed-article:4309595 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:4309595 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4309595 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4309595 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:4309595 | pubmed:issn | 0264-6021 | lld:pubmed |
| pubmed-article:4309595 | pubmed:author | pubmed-author:DaviesD DDD | lld:pubmed |
| pubmed-article:4309595 | pubmed:author | pubmed-author:RAOS NSN | lld:pubmed |
| pubmed-article:4309595 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4309595 | pubmed:volume | 113 | lld:pubmed |
| pubmed-article:4309595 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4309595 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4309595 | pubmed:pagination | 813-20 | lld:pubmed |
| pubmed-article:4309595 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:4309595 | pubmed:year | 1969 | lld:pubmed |
| pubmed-article:4309595 | pubmed:articleTitle | The effects of pH and citrate on the activity of nicotinamideA-denine dinucleotide-specific isocitrate dehydrogenase from pea mitochondria. | lld:pubmed |
| pubmed-article:4309595 | pubmed:publicationType | Journal Article | lld:pubmed |
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