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rdf:type |
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lifeskim:mentions |
umls-concept:C0003320,
umls-concept:C0009013,
umls-concept:C0014792,
umls-concept:C0019053,
umls-concept:C0022702,
umls-concept:C0025344,
umls-concept:C0205263,
umls-concept:C0871261,
umls-concept:C1254042,
umls-concept:C1533691,
umls-concept:C1561960,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C1948053,
umls-concept:C2347804,
umls-concept:C2911692
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pubmed:issue |
3
|
|
pubmed:dateCreated |
1969-10-21
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|
pubmed:abstractText |
INVESTIGATIONS OF THE INDUCTION PERIOD OF AN IN VITRO HEMOLYSIN RESPONSE TO SHEEP ERYTHROCYTE ANTIGEN REVEALED THE FOLLOWING: 1. After antigen stimulation precursors of plaque-forming cells rapidly maturate to the point of hemolysin production. 2. Initial maturation probably occurs in the absence of cell division. 3. After initial maturation, a latent period of about 12 hr occurs before the first doubling of PFC. 4. At least the first three cell doublings are synchronous, with a generation time of 7-8 hr. 5. Synchronous cell division implies that all precursor cells are at the same point in the cell cyde when they are initially stimulated.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-13945311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-16591704,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-17815805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-19867297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-4168614,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-4225815,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-4867658,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-4868775,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-4873344,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5645218,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5655473,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5666959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5691985,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5691986,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5691987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5762048,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5762049,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5909787,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5918139,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5926296,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-5929571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-6034749,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-6035276,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4241197-6060362
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pubmed:language |
eng
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pubmed:journal |
|
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0022-1007
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
543-56
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pubmed:dateRevised |
2010-9-13
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pubmed:meshHeading |
pubmed-meshheading:4241197-Animals,
pubmed-meshheading:4241197-Antigen-Antibody Reactions,
pubmed-meshheading:4241197-Antigens,
pubmed-meshheading:4241197-Cell Division,
pubmed-meshheading:4241197-Chickens,
pubmed-meshheading:4241197-Clone Cells,
pubmed-meshheading:4241197-Culture Techniques,
pubmed-meshheading:4241197-Erythrocytes,
pubmed-meshheading:4241197-Floxuridine,
pubmed-meshheading:4241197-Hemolysin Proteins,
pubmed-meshheading:4241197-Horses,
pubmed-meshheading:4241197-Kinetics,
pubmed-meshheading:4241197-Male,
pubmed-meshheading:4241197-Mice,
pubmed-meshheading:4241197-Puromycin,
pubmed-meshheading:4241197-Sheep,
pubmed-meshheading:4241197-Spleen,
pubmed-meshheading:4241197-Time Factors
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pubmed:year |
1969
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pubmed:articleTitle |
Maturation of hemolysin-producing cell clones. I. The kinetics of the induction period of an in vitro hemolysin response to erythrocyte antigen.
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pubmed:publicationType |
Journal Article
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