Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1967-4-20
pubmed:abstractText
The formation of C'1 esterase from C'1, the first component of complement, may be brought about by the action of plasmin or trypsin upon C'1s, a subcomponent of C'1. These enzymes also decrease the esterolytic activity of C'1 esterase. The formation of C'1 esterase was demonstrated by measuring the appearance of an agent or agents with esterolytic properties and the capacity to inactivate C'2 and C'4, attributes of C'1 esterase. The activity of the agent which evolved was blocked by serum inhibitor of C'1 esterase. The implications of these observations, that the formation of C'1 esterase during complement fixation is mediated by proteolytic processes, are under study. The possible inhibition of C'1q by soybean trypsin inhibitor is in agreement with this hypothesis.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13052820, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13084846, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13201755, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13336065, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13336090, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13398627, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13398628, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13435237, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13513912, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13843375, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13929797, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-13932245, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-14128991, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-14151101, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-14193148, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-14281368, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-14398764, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-14416422, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-15390425, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-19867295, http://linkedlifedata.com/resource/pubmed/commentcorrection/4225264-5855583
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0022-1007
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
125
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
337-58
pubmed:dateRevised
2010-9-13
pubmed:meshHeading
pubmed:year
1967
pubmed:articleTitle
The conversion of C'IS to C'1 esterase by plasmin and trypsin.
pubmed:publicationType
Journal Article