Linked Life Data

4218182

Source:http://linkedlifedata.com/resource/pubmed/id/4218182

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1975-6-20
pubmed:abstractText
Two hundred and ninety second chromosomes extracted from a natural population of Drosophila melanogaster were analyzed to estimate the genetic variance of viability and its components by means of a partial diallel cross (Design II of Comstock and Robinson 1952). The additive and dominance variances are estimated to be 0.009 and 0.0012. Using the dominance variance and the inbreeding depression, the effective number of overdominant loci contributing to the variance in viability is estimated to be very small, a dozen or less. Either the actual number of loci is small, or the distribution of viabilities is strongly skewed with a large majority of very weakly selected loci. The additive variance in viability appears to be too large to be accounted for by recurrent harmful mutants or by overdominant loci at equilibrium with various genetic parameters estimated independently. The excess might be due to frequency-dependent selection, to negative correlations between viability and fertility, or possibly to the presence of a mutator. The selection for viability and fertility, or possibly to the presence of a mutator. The selection for viability at the average polymorphic locus must be very slight, of the order of 10(-3) or less.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1195-208
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1974
pubmed:articleTitle
The genetic variance for viability and its components in a local population of Drosophila melanogaster.
pubmed:publicationType
Journal Article