Linked Life Data

41765

Source:http://linkedlifedata.com/resource/pubmed/id/41765

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1980-2-28
pubmed:abstractText
When injected into the amniotic sacs of fetal rats in late pregnancy, 3H-leucine is rapidly absorbed and incorporated into fetal proteins as determined by liquid scintillation spectrometry. Peak values in the fetal liver and pancreas occur around four hours after injection. Approximately 21% of the radioisotope is retained in the injected fetus at 24 hours. The remainder escapes into the maternal circulation and accounts for a gradual increase in levels in noninjected fetuses from the same litter and for persistently high counts found in maternal serum as late as 24 hours after the injection. Specific activity of the radioisotope in fetal tissues is considerably higher (100- to 200-fold) when 3H-leucine is injected inth the amniotic sac rather than intravenously into the mother. The possible treatment of various fetal disorders by means of intra-amniotic injections is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0020-7292
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
172-8
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:articleTitle
Fetal absorption of 3H-leucine injected into the amniotic sacs of pregnants rats.
pubmed:publicationType
Journal Article