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rdf:type |
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lifeskim:mentions |
umls-concept:C0014441,
umls-concept:C0020852,
umls-concept:C0021311,
umls-concept:C0025663,
umls-concept:C0086418,
umls-concept:C0205470,
umls-concept:C0242485,
umls-concept:C0441889,
umls-concept:C0450442,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2911692
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pubmed:issue |
2
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pubmed:dateCreated |
1978-5-17
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pubmed:abstractText |
The report describes the development of an enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies against the human reovirus-like agent of infantile gastroenteritis (HRVLA). This ELISA system proved to be four times as sensitive as the standard anti-HRVLA fluorescent-antibody assay and ten times as sensitive as the standard anti-HRVLA complement fixation assay. In addition, the ELISA was capable of determining immunoglobulin G (IgG) and IgM subclasses of anti-HRVLA antibody using a single dilution os serum. With this assay, it was discovered that 11 of 21 infected children had anti-HRVLA IgM in their acute sera before the appearance of anti-HRVLA IgG. ELISA is a useful tool in the evaluation of immunological response to HRVLA infection.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-1085667,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-176586,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-184047,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-192678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-194916,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-195102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-321688,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-402427,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-4202959,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-4216603,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-4568349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-4605043,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-46387,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-48729,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-54627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-61589,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-69877,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-778277,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-780003,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-785942,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-789402,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-795817,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-812805,
http://linkedlifedata.com/resource/pubmed/commentcorrection/415978-965475
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0019-9567
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
19
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
540-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:415978-Adult,
pubmed-meshheading:415978-Antibodies, Viral,
pubmed-meshheading:415978-Child,
pubmed-meshheading:415978-Complement Fixation Tests,
pubmed-meshheading:415978-Diarrhea, Infantile,
pubmed-meshheading:415978-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:415978-Fluorescent Antibody Technique,
pubmed-meshheading:415978-Gastroenteritis,
pubmed-meshheading:415978-Humans,
pubmed-meshheading:415978-Immunoenzyme Techniques,
pubmed-meshheading:415978-Immunoglobulin G,
pubmed-meshheading:415978-Immunoglobulin M,
pubmed-meshheading:415978-Viruses, Unclassified
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pubmed:year |
1978
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pubmed:articleTitle |
Immunological response to infection with human reovirus-like agent: measurement of anti-human reovirus-like agent immunoglobulin G and M levels by the method of enzyme-linked immunosorbent assay.
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pubmed:publicationType |
Journal Article,
Comparative Study
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