Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5864
pubmed:dateCreated
1973-8-21
pubmed:abstractText
Three patients with angina pectoris treated with practolol in varying doses developed a syndrome of arthralgia, particularly of the small joints of the hands, rash, fever, a raised E.S.R., and positive tests for lupus erythematosus (L.E.) cells and antinuclear antibody. The syndrome responded partly to withdrawal of the drug, but steroids were required to produce adequate symptomatic improvement. These disease features suggest that this is an example of drug-induced systemic lupus erythematosus (S.L.E.). The impaired ability of lymphocytes from these patients to transform in vitro indicates a testable hypothesis for the pathogenesis of the syndrome.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-13927984, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-14280257, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4105624, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4106884, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4143595, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4166916, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4331869, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4342971, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4898319, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-4996903, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-5015024, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-5105391, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-5123224, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-5751875, http://linkedlifedata.com/resource/pubmed/commentcorrection/4145853-5769742
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0007-1447
pubmed:author
pubmed:issnType
Print
pubmed:day
26
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
452-5
pubmed:dateRevised
2010-10-26
pubmed:meshHeading
pubmed:year
1973
pubmed:articleTitle
Systemic lupus erythematosus syndrome induced by practolol.
pubmed:publicationType
Journal Article