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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
2
|
| pubmed:dateCreated |
1980-1-19
|
| pubmed:abstractText |
The effects of calcium-gluconate infusions on renal function were studied in unanesthetised dogs. Each dog was studied during hydropenia and saline infusion. Hypercalcemia, mean serum calcium 3.85 mmol/l (hydropenia) and 3.62 mmol/l (saline infusion), increased fractional excretion of sodium (CNa/CIn), calcium (CCa/CIn), and magnesium (CMg/CIn). The increase was significantly higher in saline-expanded dogs than in hydropenic dogs. Fractional excretion of potassium (CK/CIn) was increased in hydropenia but remained unchanged in saline-expanded animals. Fractional excretion of phosphate (Cp/CIn) was not consistently changed by hypercalcemia. Fractional excretion of chloride (CCl/CIn) was markedly increased in saline-expanded dogs but was not changed in hydropenia. Urine osmolality was reduced in hydropenic dogs but unchanged in saline-expanded dogs. In hydropenic as well as in saline-expanded dogs tubular reabsorption of solute-free water (TcH2O/CIn) increased during the first hour of hypercalcemia. In hydropenic dogs hypercalcemia caused a slight but significant decrease in blood pH, standard bicarbonate, and base excess. In hydropenic as well as in saline-expanded dogs glomerular filtration rate (CIn), renal plasma flow (CPAH), and filtration fraction were unaffected.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0001-6772
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
106
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
177-86
|
| pubmed:dateRevised |
2003-11-14
|
| pubmed:meshHeading |
pubmed-meshheading:41408-Acid-Base Equilibrium,
pubmed-meshheading:41408-Animals,
pubmed-meshheading:41408-Bicarbonates,
pubmed-meshheading:41408-Body Water,
pubmed-meshheading:41408-Calcium Gluconate,
pubmed-meshheading:41408-Dogs,
pubmed-meshheading:41408-Female,
pubmed-meshheading:41408-Glomerular Filtration Rate,
pubmed-meshheading:41408-Hydrogen-Ion Concentration,
pubmed-meshheading:41408-Hypercalcemia,
pubmed-meshheading:41408-Infusions, Parenteral,
pubmed-meshheading:41408-Kidney,
pubmed-meshheading:41408-Osmolar Concentration,
pubmed-meshheading:41408-Oxygen Consumption,
pubmed-meshheading:41408-Partial Pressure,
pubmed-meshheading:41408-Regional Blood Flow,
pubmed-meshheading:41408-Sodium Chloride,
pubmed-meshheading:41408-Water-Electrolyte Balance
|
| pubmed:year |
1979
|
| pubmed:articleTitle |
Renal function in hypercalcemic dogs during hydropenia and during saline infusion.
|
| pubmed:publicationType |
Journal Article
|