Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1978-3-29
pubmed:abstractText
The patients studied were diagnosed as suffering from alpha-chain disease by their clinicopathological features, malabsorption findings, X-ray, and presence of abnormal alpha-chain protein in their serum. The objective of the study was to determine any possible defect of the immune system in such patients. The rosette technique and surface immunofluorescence were used to enumerate the circulating T and B lymphocytes in these patients. They were also skin-tested with tuberculin and given sensitizing doses of dinitrochlorobenzene. Their serum immunoglobulins were also quantitated. It was found that the proportion of circulating B lymphocytes was much higher than normal, whereas that of T lymphocytes was lower than normal. Furthermore, they could not be sensitized to DNCB and their skin test to tuberculin was negative. It was concluded that the disease was a B-cell disease of IgA type, associated with low level of cellular immunity.
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-128429, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4114496, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4116764, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4118467, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4119805, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4177362, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4186690, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4269268, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4919141, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4919259, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4956917, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-4982231, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-5003015, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-5031243, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-5715198, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-810150, http://linkedlifedata.com/resource/pubmed/commentcorrection/413562-826361
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0007-0920
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
48-54
pubmed:dateRevised
2009-11-18
pubmed:meshHeading
pubmed:year
1978
pubmed:articleTitle
T and B lymphocytes in alpha-chain disease.
pubmed:publicationType
Journal Article