| pubmed-article:4133781 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4133781 | lifeskim:mentions | umls-concept:C1512977 | lld:lifeskim |
| pubmed-article:4133781 | lifeskim:mentions | umls-concept:C0007586 | lld:lifeskim |
| pubmed-article:4133781 | lifeskim:mentions | umls-concept:C0005740 | lld:lifeskim |
| pubmed-article:4133781 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:4133781 | lifeskim:mentions | umls-concept:C0441655 | lld:lifeskim |
| pubmed-article:4133781 | lifeskim:mentions | umls-concept:C0040223 | lld:lifeskim |
| pubmed-article:4133781 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:4133781 | pubmed:dateCreated | 1974-7-20 | lld:pubmed |
| pubmed-article:4133781 | pubmed:abstractText | Bleomycin inhibits cell division in HeLa S-3 and other mammalian epithelial cell lines. Its effect on suspension cultured cells is far greater than on monolayer cells; this was found to be due partly to the absence of divalent ions. Other mammalian epithelial lines in suspension culture are very sensitive but fibroblastic cells (BHK 21/C13/DWS-3) grown under identical conditions are relatively insensitive. This study has established that bleomycin is a powerful anti-mitotic agent during the G(2) phase but it does not prevent prophase cells from completing a normal mitotic division. Its ability to suppress DNA synthesis contributes little to the inhibition of cell cycling. | lld:pubmed |
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| pubmed-article:4133781 | pubmed:language | eng | lld:pubmed |
| pubmed-article:4133781 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:4133781 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4133781 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4133781 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:4133781 | pubmed:issn | 0007-0920 | lld:pubmed |
| pubmed-article:4133781 | pubmed:author | pubmed-author:KajiwaraKK | lld:pubmed |
| pubmed-article:4133781 | pubmed:author | pubmed-author:MuellerG CGC | lld:pubmed |
| pubmed-article:4133781 | pubmed:author | pubmed-author:WheatleyD NDN | lld:pubmed |
| pubmed-article:4133781 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4133781 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:4133781 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4133781 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4133781 | pubmed:pagination | 117-31 | lld:pubmed |
| pubmed-article:4133781 | pubmed:dateRevised | 2011-7-20 | lld:pubmed |
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| pubmed-article:4133781 | pubmed:year | 1974 | lld:pubmed |
| pubmed-article:4133781 | pubmed:articleTitle | Anti-mitotic activity of bleomycin: time of action in the mammalian cell cycle. | lld:pubmed |
| pubmed-article:4133781 | pubmed:publicationType | Journal Article | lld:pubmed |
