| pubmed-article:4132531 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C0042776 | lld:lifeskim |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C0007600 | lld:lifeskim |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C0456387 | lld:lifeskim |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C1883725 | lld:lifeskim |
| pubmed-article:4132531 | lifeskim:mentions | umls-concept:C0591833 | lld:lifeskim |
| pubmed-article:4132531 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:4132531 | pubmed:dateCreated | 1974-6-12 | lld:pubmed |
| pubmed-article:4132531 | pubmed:abstractText | The existence of the selectively permissive rabbit cell line SIRC allows definition of a new class of endogenous murine type-C virus. Continuous clonal lines of transformed cells derived from the BALB/c mouse-embryo cell line BALB/3T3 contain at least two distinct classes of endogenous type-C viral genomes. Spontaneously released endogenous viruses grow well on the mouse cell line NIH/3T3 (N-tropic viruses) but not on the rabbit cell line SIRC. Type-C viruses induced by treatment with BrdU grow well on SIRC (S-tropic viruses) but not in NIH/3T3 or BALB/3T3. BrdU-treated AKR mouse-embryo cells also release an S-tropic virus. N-tropic and S-tropic viruses both have the mouse intraspecies gs-1 and viral RNA-directed DNA polymerase antigenic determinants. DNA.RNA hybridization techniques reveal that the two host-range classes of endogenous viruses are only partially related to each other. Cell transformation facilitates the spontaneous release of the N-tropic viruses; treatment with thymidine analogues induces the production of the S-tropic viruses. Thus, the two classes of viral genomes appear to be subject to different cellular controls. | lld:pubmed |
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| pubmed-article:4132531 | pubmed:language | eng | lld:pubmed |
| pubmed-article:4132531 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:4132531 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:4132531 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:4132531 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:4132531 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:4132531 | pubmed:author | pubmed-author:TodaroG JGJ | lld:pubmed |
| pubmed-article:4132531 | pubmed:author | pubmed-author:LieberM MMM | lld:pubmed |
| pubmed-article:4132531 | pubmed:author | pubmed-author:BenvenisteR... | lld:pubmed |
| pubmed-article:4132531 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:4132531 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:4132531 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:4132531 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:4132531 | pubmed:pagination | 602-6 | lld:pubmed |
| pubmed-article:4132531 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:4132531 | pubmed:year | 1974 | lld:pubmed |
| pubmed-article:4132531 | pubmed:articleTitle | A distinct class of inducible murine type-C viruses that replicates in the rabbit SIRC cell line. | lld:pubmed |
| pubmed-article:4132531 | pubmed:publicationType | Journal Article | lld:pubmed |
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