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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1974-6-12
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pubmed:abstractText |
The existence of the selectively permissive rabbit cell line SIRC allows definition of a new class of endogenous murine type-C virus. Continuous clonal lines of transformed cells derived from the BALB/c mouse-embryo cell line BALB/3T3 contain at least two distinct classes of endogenous type-C viral genomes. Spontaneously released endogenous viruses grow well on the mouse cell line NIH/3T3 (N-tropic viruses) but not on the rabbit cell line SIRC. Type-C viruses induced by treatment with BrdU grow well on SIRC (S-tropic viruses) but not in NIH/3T3 or BALB/3T3. BrdU-treated AKR mouse-embryo cells also release an S-tropic virus. N-tropic and S-tropic viruses both have the mouse intraspecies gs-1 and viral RNA-directed DNA polymerase antigenic determinants. DNA.RNA hybridization techniques reveal that the two host-range classes of endogenous viruses are only partially related to each other. Cell transformation facilitates the spontaneous release of the N-tropic viruses; treatment with thymidine analogues induces the production of the S-tropic viruses. Thus, the two classes of viral genomes appear to be subject to different cellular controls.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-13985244,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-14331182,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4113509,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4118366,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4120907,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4122307,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4123693,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4123998,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4125845,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4126409,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4133949,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4311790,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4317349,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4330367,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4332980,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4333537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4338992,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4347595,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4352968,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4355218,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4357865,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4359949,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4626657,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-4633070,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-5119627,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-5309096,
http://linkedlifedata.com/resource/pubmed/commentcorrection/4132531-5918951
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0027-8424
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
71
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
602-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:4132531-Animals,
pubmed-meshheading:4132531-Antigens, Viral,
pubmed-meshheading:4132531-Cats,
pubmed-meshheading:4132531-Cell Line,
pubmed-meshheading:4132531-Clone Cells,
pubmed-meshheading:4132531-Cornea,
pubmed-meshheading:4132531-Fibroblasts,
pubmed-meshheading:4132531-Haplorhini,
pubmed-meshheading:4132531-Humans,
pubmed-meshheading:4132531-Mice,
pubmed-meshheading:4132531-Mice, Inbred BALB C,
pubmed-meshheading:4132531-Nucleic Acid Hybridization,
pubmed-meshheading:4132531-RNA, Viral,
pubmed-meshheading:4132531-RNA-Directed DNA Polymerase,
pubmed-meshheading:4132531-Rabbits,
pubmed-meshheading:4132531-Rats,
pubmed-meshheading:4132531-Retroviridae,
pubmed-meshheading:4132531-Species Specificity,
pubmed-meshheading:4132531-Thymidine,
pubmed-meshheading:4132531-Tritium,
pubmed-meshheading:4132531-Virus Cultivation,
pubmed-meshheading:4132531-Virus Replication
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pubmed:year |
1974
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pubmed:articleTitle |
A distinct class of inducible murine type-C viruses that replicates in the rabbit SIRC cell line.
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pubmed:publicationType |
Journal Article
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