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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
1977-12-29
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pubmed:abstractText |
The effects of thyrotropin-releasing hormone (TRH) and dopamine (DA) on serum growth hormone (GH) levels were examined in the adolescent male baboon. Intravenously administered DA (40 microgram/kg-min-1 for 20 min) raised serum GH and glucose and lowered serum insulin concentrations but caused no increase in blood pressure. Concomitant intravenous infusion of TRH at 2 doses (96 ng/kg-min-1 and 40 microgram/kg-min-1 for 20 min) blocked the DA-induced increase in serum GH. The relatively low effective doses of TRH used to suppress the DA-induced GH increase suggest an interaction with catecholamines at the hypothalamic and/or pituitary to influence GH release.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0002-9513
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
233
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
E430-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:411377-Animals,
pubmed-meshheading:411377-Blood Glucose,
pubmed-meshheading:411377-Blood Pressure,
pubmed-meshheading:411377-Dopamine,
pubmed-meshheading:411377-Dopamine Antagonists,
pubmed-meshheading:411377-Growth Hormone,
pubmed-meshheading:411377-Haplorhini,
pubmed-meshheading:411377-Insulin,
pubmed-meshheading:411377-Male,
pubmed-meshheading:411377-Papio,
pubmed-meshheading:411377-Thyrotropin-Releasing Hormone
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pubmed:year |
1977
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pubmed:articleTitle |
Inhibition of dopamine-induced release of growth hormone by thyrotropin-releasing hormone.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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