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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
11
|
| pubmed:dateCreated |
1977-12-29
|
| pubmed:abstractText |
A catechol metabolite, 5-(3,4-dihydroxyphenyl)-5-phenylhydantoin, and a methylated catechol metabolite, 5-(3-methoxy-4-hydroxyphenyl)-5-phenylhydantoin, were identified as urinary metabolites in humans, monkeys, and dogs following the administration of phenytoin. These metabolites were separated from each other and from other known metabolites of phenytoin as n-butyl derivatives by GLC and positively identified by combined GLC-mass spectrometry.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Nov
|
| pubmed:issn |
0022-3549
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
66
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1596-602
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:410919-Animals,
pubmed-meshheading:410919-Biotransformation,
pubmed-meshheading:410919-Catechols,
pubmed-meshheading:410919-Chromatography, Gas,
pubmed-meshheading:410919-Dogs,
pubmed-meshheading:410919-Haplorhini,
pubmed-meshheading:410919-Humans,
pubmed-meshheading:410919-Macaca mulatta,
pubmed-meshheading:410919-Male,
pubmed-meshheading:410919-Mass Spectrometry,
pubmed-meshheading:410919-Phenytoin
|
| pubmed:year |
1977
|
| pubmed:articleTitle |
Identification of urinary catechol and methylated catechol metabolites of phenytoin in humans, monkeys, and dogs by GLC and GLC-mass spectrometry.
|
| pubmed:publicationType |
Journal Article
|