Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
12
pubmed:dateCreated
1986-4-7
pubmed:abstractText
In the order to gain further insight into the sensory nervous pathways during enflurane- and isoflurane anaesthesia, two different concentrations (1 and 2 vol.%) of the anaesthetics were given to patients during extracorporeal circulation in normothermia and normocarbia, while somatosensory-evoked potentials (SEP) were recorded. As SEP-changes either reflect a change in functional integrity of the sensory nervous pathways (amplitude suppression) and a change in the speed of conduction (latency changes), the central effects of the volatile anaesthetics could be more fully evaluated. Isoflurane as well as enflurane induced a concentration-related change in latency especially of the late N100-component. However, in contrast to isoflurane administration the isomer enflurane in the high concentration range (2 vol.%) induced an increase of amplitudes of the early N20 and late N100-peak. Such an increase in amplitudes is interpreted as a disinhibition of medullary inhibitory centres, a possible premonitory sign of epileptogenic cortical activity, which already had been observed by various investigators.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0003-2417
pubmed:author
pubmed:issnType
Print
pubmed:volume
34
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
670-4
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
[Somatosensory evoked potentials (SEP) by isoflurane and enflurane in cardiosurgical interventions].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract