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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
12
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pubmed:dateCreated |
1986-4-7
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pubmed:abstractText |
In the order to gain further insight into the sensory nervous pathways during enflurane- and isoflurane anaesthesia, two different concentrations (1 and 2 vol.%) of the anaesthetics were given to patients during extracorporeal circulation in normothermia and normocarbia, while somatosensory-evoked potentials (SEP) were recorded. As SEP-changes either reflect a change in functional integrity of the sensory nervous pathways (amplitude suppression) and a change in the speed of conduction (latency changes), the central effects of the volatile anaesthetics could be more fully evaluated. Isoflurane as well as enflurane induced a concentration-related change in latency especially of the late N100-component. However, in contrast to isoflurane administration the isomer enflurane in the high concentration range (2 vol.%) induced an increase of amplitudes of the early N20 and late N100-peak. Such an increase in amplitudes is interpreted as a disinhibition of medullary inhibitory centres, a possible premonitory sign of epileptogenic cortical activity, which already had been observed by various investigators.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Dec
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pubmed:issn |
0003-2417
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
670-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:4096359-Afferent Pathways,
pubmed-meshheading:4096359-Anesthesia, Inhalation,
pubmed-meshheading:4096359-Enflurane,
pubmed-meshheading:4096359-Evoked Potentials, Somatosensory,
pubmed-meshheading:4096359-Heart Diseases,
pubmed-meshheading:4096359-Humans,
pubmed-meshheading:4096359-Isoflurane,
pubmed-meshheading:4096359-Median Nerve,
pubmed-meshheading:4096359-Methyl Ethers,
pubmed-meshheading:4096359-Reaction Time,
pubmed-meshheading:4096359-Somatosensory Cortex
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pubmed:year |
1985
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pubmed:articleTitle |
[Somatosensory evoked potentials (SEP) by isoflurane and enflurane in cardiosurgical interventions].
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pubmed:publicationType |
Journal Article,
Comparative Study,
English Abstract
|