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pubmed:abstractText |
In strain HK187 (Streptococcus faecalis subsp. liquefaciens) four plasmids were isolated. The molecular weights, as analyzed in neutral sucrose gradients and by electron microscopy, were found to be about 36 x 10(6), 31 x 10(6), 26 x 10(6), and 4 x 10(6). Plasmid 3, also designated pFK14, with a molecular weight of 26 x 10(6), was found to be responsible for resistance to chloramphenicol and erythromycin and also for high-level resistance to streptomycin and lincomycin. In mixed cultures these four resistances could be transferred with high frequency to a plasmid-free recipient, S. faecalis strain JH2-2.
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