Linked Life Data

4092898

Source:http://linkedlifedata.com/resource/pubmed/id/4092898

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6 Pt 2
pubmed:dateCreated
1986-4-8
pubmed:abstractText
The functional set-up of a static inhalation device is described. The closed system consists of a reservoir for the circulating test gas, an inhalator for "nose-only" exposure of 10 rats, and analyzers for the test gas and CO2. It has an overall volume of 200 liters. The following LCt50 values for rats exposed to noxious vapors were determined: DFP 3629, sarin 191, and soman 211 mg X min X m-3. Pretreatment with atropine (10 mg/kg) together with the oximes Toxogonin or HJ6 (each 13 mg/kg) 10 min before the exposure raised the LCt50 of sarin by a factor of 2.5 and 14, respectively. In case of soman poisoning, only HJ6 (50 mg/kg) together with atropine was effective, which increased the LCt50 by a factor of 7.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0272-0590
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S84-8
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
The protective effect of oxime pretreatment upon the inhalative toxicity of sarin and soman in rats.
pubmed:publicationType
Journal Article