Linked Life Data

4091858

Source:http://linkedlifedata.com/resource/pubmed/id/4091858

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1986-3-26
pubmed:abstractText
It has been postulated that sulphatides may be the K+ binding site of the sodium pump. In order to test this hypothesis we studied the binding of K+ to bilayer membranes containing sulphatides or phosphatidylserine. The adsorption constants of Na+, K+ and Ca2+ to planar bilayers containing these acidic lipids were determined from changes in the electrostatic potential at the membrane surface. Our results indicate that univalent cations adsorb weakly to both lipids and Ca2+ binds more strongly. The sequence of ion binding was Ca2+ greater than Na+ greater than K+. These results indicate that K+ does not bind specifically to sulphatides or phosphatidylserine and rule out the proposal that sulphatides by themselves provide the K+ binding site of the sodium pump.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0158-5231
pubmed:author
pubmed:issnType
Print
pubmed:volume
11
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
863-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Adsorption of uni and divalent cations to planar bilayer membranes containing sulphatides or phosphatidylserine.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't