Linked Life Data

4086338

Source:http://linkedlifedata.com/resource/pubmed/id/4086338

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1986-2-28
pubmed:abstractText
The origin and the structure of the limiting membranes of autophagic vacuoles (AV) in mouse hepatocytes was studied using cytochemical techniques. Autophagocytosis was induced by an intraperitoneal injection of vinblastine (50 mg/kg). Imidazole-buffered osmium tetroxide impregnation was used as a marker for unsaturated fatty acids, and uranyl-lead-copper impregnation for the determination of possible connections of AV membranes with the other cellular membranes. AV membranes stained strongly with both techniques. The staining pattern of AV membranes differed from that of the other cellular membranes. AV's were frequently seen to fuse with vesicles containing very low density lipoprotein particles. No other connections of AV membranes with other cellular membranes were observed. The results suggest that if pre-existing cellular membranes are used in AV formation some kind of transformation must occur in these membranes during AV formation. The content of unsaturated fatty acids appears to be high in AV membranes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0301-5564
pubmed:author
pubmed:issnType
Print
pubmed:volume
83
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
513-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1985
pubmed:articleTitle
Studies on vinblastine-induced autophagocytosis in mouse liver. V. A cytochemical study on the origin of membranes.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't